General Cell Lines and Cell Cultures
ATCC Chlamydia trachomatis; Serovar Ba; Strain: Apache-2
Chlamydia trachomatis Serovar Ba strain Apache-2 is propagated in McCoy [McCoy B] cells (ATCC CRL-1696). This strain was isolated from the eye of a child from the Apache tribe in San Carlos, Arizona. This product has applications in sexually transmitted disease and trachoma research.
Eurofins Discoverx ChemiScreen V2 Vasopressin Receptor Stable Cell Line, 2 vials. (HTS060C)
The ChemiScreen V2 Vasopressin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay V2 Vasopressin Receptor Frozen Cells, 2 Vials of Cells. (HTS060RTA)
The Ready-to-Assay V2 Vasopressin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen ETB Endothelin Receptor Stable Cell Line, 2 vials. (HTS046C)
The ChemiScreen ETB Endothelin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. endothelin) based activation of EDNRB GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses EDNRB alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of EDNRB, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen CCR9 Chemokine Receptor Membrane Preparation, 1 vial. (HTS036M)
The ChemiScreen CCR9 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CCR9 surface expression. ChemiScreen membrane preps can be used to screen for GPCR activity using GTPγS assays. Increased GPCR activation levels will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx Ready-to-Assay GPR54/KiSS1 Receptor Frozen Cells, 2 Vials of Cells. (HTS032RTA)
The Ready-to-Assay GPR54/KiSS1 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand based activation of KISS1R GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses KISS1R alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of KISS1R, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
ATCC UACC-812; Breast Ductal Carcinoma; Human (Homo sapiens)
UACC-812 is a cell line exhibiting epithelial-like morphology that was isolated from the mammary gland of a White, 43-year-old, female patient with ductal carcinoma. This cell line was deposited by A Liebovitz, J Trent, and can be used in cancer research.
ATCC Quantitative Genomic DNA from; Prevotella bivia; Strain: VPI 6822
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Candida albicans; Y537
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Saccharomyces cerevisiae; BY4733
An ampoule containing viable cells suspended in cryoprotectant.
