General Cell Lines and Cell Cultures
Cayman Chemical GPR120 Compound A 1mg
An orally available, selective agonist of GPR120 (EC50 = ~0.35 µM); exerts anti-inflammatory effects on macrophages in vitro and improves glucose tolerance, decreases hyperinsulinemia, increases insulin sensitivity, and decreases hepatic steatosis when included at 30 mg/kg body weight in a high-fat diet fed to obese mice
Eurofins Discoverx ChemiScreen V2 Vasopressin Receptor Stable Cell Line, 2 vials. (HTS060C)
The ChemiScreen V2 Vasopressin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. vasopressin) based activation of AVPR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses AVPR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Promocell GmbH PromoCell HUAEC-c 500,000 Human Umbilical Artery Endothelial Cells, cryopreserved
Primary Human Umbilical Artery Endothelial Cells (HUAEC) are isolated from the arteries of the umbilical cord and are often used for in vitro studies on atherosclerosis but also for endothelial cell-dependent lymphocyte activation and chemoattractant activity experiments.Available formats:* Cryopreserved: Cryogenic vial containing 500.000 viable cells.* Proliferating: >500.000 viable cells shipped in growth medium (T25 flask).* Cell pellet: 1 million cells dissolved in 200µl RNAlater© for subsequent RNA, DNA or protein analysis. Cell pellets cannot be revived.
Eurofins Discoverx PathHunter U2OS MC1R β-Arrestin Cell Line, 2 vials. (93-0861C3)
The PathHunter MC1R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of MC1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC1R and EA-tagged β-Arrestin-2. Activation of MC1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Candida glabrata
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
Eurofins Discoverx cAMP Hunter CHO-K1 CXCR3 Gi Cell Line, 2 vials. (95-0054C2)
The cAMP Hunter CXCR3 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. CXCL11/I-TAC) based activation of CXCR3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type CXCR3, a naturally Gi/Go coupled GPCR. Upon activation of CXCR3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC 293; Embryonic Kidney; Genomic DNA, Human
High molecular weight genomic DNA isolated from the 293 human embryonal kidney cell line transformed with adenovirus 5 DNA (ATCC CRL-1573).
Hach Company Pool Master Test Kit
Hach's Pool Master Test Kit combines several tests into a single test kit. The test kit includes tests for alkalinity (20-400 mg/L), free and total chlorine (0-3.4 mg/L), hardness (20-400 mg/L), and pH (6.6-8.4 mg/L), plus specialized tests for total alkalinity, calcium hardness, and cyanuric acid.
ATCC SKW 6.4; B Lymphoblast; Human (Homo sapiens)
SKW 6.4 is a B lymphocyte cell that was isolated from the spleen of a mouse with leukemia and can be used in immunology research.
ATCC HT-29; Colon Adenocarcinoma; Genomic DNA, Human
High molecular weight genomic DNA isolated from the HT-29; human colorectal carcinoma cell line.
ATCC Streptococcus pyogenes; group a, type 38
Streptococcus pyogenes typing strain C94 is serotype 38 and is classified as Lancefield's group A. This aerobic bacterium can be used in emerging infectious disease research.
ATCC Ramos (RA 1); Burkitt's Lymphoma; Human (Homo sapiens)
Ramos (RA 1) is a B lymphocyte cell line that was derived from a 3-year-old, White, male patient with Burkitt’s Lymphoma (American). This cell line can be used in immunology research.
Eurofins Discoverx PathHunter CHO-K1 mFPR1 β-Arrestin Cell Line, 2 vials. (93-0570C2)
The PathHunter mFPR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. formylpeptides) based activation of mFPR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mFPR1 and EA-tagged β-Arrestin-2. Activation of mFPR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Biochain Institute Inc Matched Pair - Total RNA - Human Primary and Metastatic Tumor Tissue: Kidney, 2x10 ug/PK
BioChain's human total RNA matched pair products include: Primary Pair (PP), Primary and Metastatic Pair (PM). PP consists of total RNA isolated from primary tumor and its adjacent normal tissue; PM consists of total RNA from primary tumor and and corresponding metastatic tumor. Total RNA in each pair is prepared from the same donor. This product line is designed for identifying tumor-specific genes and tumor metastatic genes.